I find I have to hold over about 12" at 100 yards with my 10/22 shooting standard velocity ammo. It is however zero'd for 25 yards. I found charts claiming everything from 5.5" drop, to 7" drop to almost 13" drop as here:
http://www.gunsmoke.com/guns/1022/images/22hv_table.gif
Take your pic. Personally I think 22LR is silly at 100 yards.